Project C4 (PIs Rainey, Hentschel) aims to explore the role of mobile genetic elements (MGEs) as regulators of host-associated microbial community composition and function. The project will build on the established Metaorganism Evolution Experiment (MEE) approach to provide detailed insights into the dynamics of evolutionary change under conditions that either promote or hinder MGEs in two host-microbe pairs: the worm C. elegans and Ochrobactrum, and the sponge H. panicea and Vibrio.
C4
Function and Life History
New approaches to understanding eco-evolutionary dynamics in metaorganisms
C4
Researchers
Researchers
C4.2 (E): Phages and their functional role in the acclimatisation of Hydra to changing environmental conditions
C4
C4
C4
C4.3: Understanding phage dynamics and function in marine sponges
C4
B1
C4
C4: Alumni
C4
C4
Related Publications
Related Publications
2024
C4
von Hoyningen-Huene AJE, Bang C, Rausch P, Rühlemann M, Fokt H, He J, Jensen N, Knop M, Petersen C, Schmittmann L, Zimmer T, Baines JF, Bosch TCG, Hentschel U, Reusch TBH, Roeder T, Franke A, Schulenburg H, Stukenbrock E and Schmitz RA (2024) The archaeome in metaorganism research, with a focus on marine models and their bacteria– archaea interactions. Front Microbiol, 15:1347422. doi: 10.3389/fmicb.2024.1
2024
C4
Maribacter Halichondriae sp. nov., isolated from the marine sponge Halichondria panicea displays features of a sponge‑associated life style
Steiner LX, Wiese J, Rahn T, Borchert E, Slaby B, Hentschel U (2024) Maribacter Halichondriae sp. nov., isolated from the marine sponge Halichondria panicea displays features of a sponge‑associated life style. Antonie Van Leeuwenhoek, Mar 15;117(1):56. https://doi.org/10.1007/s10482-024-01950-4
2022
B1
C4
Sponge-symbiont stability in spite of antibiotic-induced microbiome disturbance
Schmittmann L, Rahn T, Busch K, Fraune S, Pita L, Hentschel U. (2022) Environ. Microbiol. 24: 6392-6410, https://doi.org/10.1111/1462-2920.16249
2022
C4
Adaptive lifestyle of bacteria determines phage-bacteria interaction
Ulrich Laura, Giez Christoph, Steiner Leon X., Hentschel Ute, Lachnit Tim (2022): Frontiers in Microbiology, Vol 13.
https://www.frontiersin.org/articles/10.3389/fmicb.2022.1056388
2022
B1
C1
C4
Symbiotic Algae of Hydra viridissima Play a Key Role in Maintaining Homeostatic Bacterial Colonization.
Bathia J, Schröder K, Fraune S, Lachnit T, Rosenstiel P, Bosch TCG (2022) Front. Microbiol. 13:869666. doi: 10.3389/fmicb.2022.869666
2022
C1
C4
Hydra and the hair follicle – An unconventional comparative biology approach to exploring the human holobiont.
Lousada MB, Lachnit T, Edelkamp J, Paus R, Bosch TCG (2022 ) Bioessays. 44(5):e2100233. doi: 10.1002/bies.202100233.
2022
C4
Cacatoo: building, exploring, and sharing spatially structured models of biological systems.
van Dijk B (2022) Journal of Open Source Software, 7(70), 3948, doi: 10.21105/joss.03948
2021
C4
Transposable elements promote the evolution of genome streamlining
van Dijk B, Bertels F, Stolk L, Takeuchi N, Rainey PB (2021) Phil. Trans. R. Soc. B. 377:20200477. doi: 10.1098/rstb.2020.0477
2021
B1
C4
Featured
Harnessing the power of host–microbe symbioses to address grand challenges.
Hentschel U (2021) Nat Rev Microbiol. 19, 615–616. doi: 10.1038/s41579-021-00619-3
2021
B1
C4
Featured
Lifestyle of sponge symbiont phages by host prediction and correlative microscopy
Jahn MT, Lachnit T, Markert SM, Stigloher C, Pita L, Ribes M, Dutilh BE, Hentschel U (2021) ISME J. doi: 10.1038/s41396-021-00900-6