Identification of diacylated ureas as a novel family of fungus-specific leukocyte-activating pathogen-associated molecules.

Schröder J M, Häsler R, Grabowsky J, Kahlke B, Mallet A I (2002); J Biol Chem., 277(31):27887-95.

Ratios of radical to conservative amino acid replacement are affected by mutational and compositional factors and may not be indicative of positive Darwinian selection. NK-lysin and its shortened analog NK-2 exhibit potent activities against Trypanosoma cruzi.