The
membrane-proximal domain of ADAM17 represents the putative molecular switch of its shedding activity
operated by protein-disulfide isomerase.

Düsterhöft S, Jung S, Hung C W, Tholey A, Sönnichsen F D, Grötzinger J, Lorenzen I (2013); J Am Chem Soc, 135:5776-5781. doi: 10.1021/ja400340u

Institutions & Partners

By continuing to use the site, you agree to the use of cookies and our privacy policy.