Dr. Mike Taylor (University of Auckland)

Invited guest speaker at the Biology Center of the Christian-Albrechts-University Kiel

Thursday, August 23rd 2018, 16:15

Conference room 4th floor
Am Botanischen Garten 11

As guest of the CRC 1182

Dr. Mike Taylor

(University of Auckland, New Zealand)

Talks about:

“The airway microbiota in health and disease”


The airway microbiota is an under-explored microbial community relevant to both health and disease.  While a microbial role is likely in many airway diseases, the exact nature of the host-microbe interaction often remains unclear.  I will present two lines of recent research from my lab: (1) the microbiome in adults with chronic sinus disease, and (2) the paediatric lung microbiota in non-cystic fibrosis bronchiectasis.  Chronic rhinosinusitis (CRS) is a common, debilitating condition characterised by long-term inflammation of the nasal cavity and paranasal sinuses.  It affects ~5% of adults and annual treatment costs associated with CRS exceed US$8.6 billion in the USA alone.  Our data suggest that, rather than a simple one pathogen, one disease model, CRS may be associated with a breakdown, or dysbiosis, of the entire microbial community.  Such a shift in microbiota composition may in turn drive an exacerbated and ongoing inflammatory response.  By contrast, the diversity of the lung microbiota in children with non-CF bronchiectasis appears to be largely retained, at least at the point of disease diagnosis.  I will present results derived from 16S rRNA gene amplicon sequencing, immunological assays and ecological network analyses, and will discuss potential clinical implications of our findings.


Dr. Mike Taylor (University of Auckland)


August 23rd, 2018


Conference room 4th floor

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