Principal Investigator

Dr. Sebastian Fraune

Vita

Education/Training

12/2005 – 01/2009
Dissertation at the Christian-Albrechts University of Kiel, Zoological Institute, (supervised by Prof. Dr. Dr. h.c. Bosch), Title: Towards understanding a holobiont: Host-microbe interaction in Hydra; “summa cum laude”

1999 – 2005
Diploma Biology (Microbiology, Limnology, Toxicology), Christian-Albrechts University of Kiel, Germany


Research Experience/Academic Appointments

since 2012
Assistant Project Manager for the laboratory of Prof. Bosch to work with genetically-modified organisms (S1)

since 02/2009
Postdoctoral Fellow, Zoological Institute, Christian-Albrechts-University of Kiel, Germany, group of Prof. Dr. Dr. h.c. Thomas Bosch


Important Scientific Prizes/Functions

since 2013
Editorial service for scientific journal: Frontiers in Microbial Symbiosis – Associate Editor

since 2012
Referee service for scientific journals: Environmental Microbiology, PLoS ONE, Marine Biology, Bioessays, Frontiers in Microbial Symbiosis

2011
Awards: Poster Prize, Gordon Research Conference Antimicrobial Peptides in Innate Immunity – New Insights on an Ancient System

2008
Travel grant to participate at the 2nd ASM Conference on Beneficial Microbes, San Diego (USA)

Research

Publications

2018

Metabolic co-dependence drives the evolutionarily ancient Hydra-Chlorella symbiosis.

Hamada M, Schröder K, Bathia J, Kürn U, Fraune S, Khalturina M, Khalturin K, Shinzato C, Satoh N, Bosch TC (2018); Elife 7. pii: e35122. doi: 10.7554/eLife.35122

Carrying capacity and colonization dynamics of Curvibacter in the Hydra host habitat

Wein T, Dagan T, Fraune S, Bosch TCG, Reusch TBH and Hülter NF (2018) Front. Microbiol.https://doi.org/10.3389/fmicb.2018.00443

Predicted bacterial interactions affect in vivo microbial colonization dynamics in Nematostella

Domin H, Zurita-Gutiérrez Y, Scotti M, Buttlar J, Hentschel Humeida U and Fraune S  (2018) Frontiers in Microbiology 9, 728, https://doi.org/10.3389/fmicb.2018.00728

Stem cell transcription factor FoxO controls microbiome resilience in Hydra.

Mortzfeld B M, Taubenheim J,Fraune S, Klimovich A V, Bosch T C G (2018); Front Microbiol., in press

Metaorganisms in extreme environments: do microbes play a role in organismal adaptation?

Bang C, Dagan T, Deines P, Dubilier N, Duschl W J, Fraune S, Hentschel U, Hirt H, Hülter N, Lachnit T, Picazo D, Galan P L, Pogoreutz C, Rädecker N, Saad M M, Schmitz R A, Schulenburg H, Voolstra C R, Weiland-Bräuer N, Ziegler M, Bosch T C G (2018); Zoology, doi: 10.1016/j.zool.2018.02.004

2017

Temperate phages as self-replicating weapons in bacterial competition.

Li XY, Lachnit T, Fraune S, Bosch T C G, Traulsen A, Sieber M (2017); J R Soc Interface, 14(137). doi: 10.1098/rsif.2017.0563

FeaturedA secreted antibacterial neuropeptide shapes the microbiome of Hydra.

Augustin R, Schröder K, Murillo Rincón A P, Fraune S, Anton-Erxleben F, Herbst E M, Wittlieb J, Schwentner M, Grötzinger J, Wassenaar T M, Bosch T C G (2017); Nat Commun., 8(1):698. doi: 10.1038/s41467-017-00625-1

Temperate phages as frequency-dependent weapons in bacterial competition.

Li X Y, Lachnit T, Fraune S, Bosch T C G, Traulsen A, Sieber M (2017); j r soc interface, doi: 10.1101/185751

2016

Emerging Sponge Models of Animal-Microbe Symbioses.

Pita L, Fraune S, Hentschel U (2016); Front Microbiol., 7:2102. doi: 10.3389/fmicb.2016.02102

Using Nematostella vectensis to Study the Interactions between Genome, Epigenome, and Bacteria in a Changing Environment.

Fraune S, Forêt S, Reitzel A M (2016); Front. Mar. Sci., 3:148. doi: 10.3389/fmars.2016.00148